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安乳颗粒中丹参的乙醇提取试验研究

Study on the Extracting Procedure of Salvia miltiorrhiza in Anru keli

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【作者】 范彬石晓峰沈薇黄钰芳马趣环张芳红

【Author】 Fan Bin,Shi Xiaofeng,Shen Wei,Huang Yufang1,Ma Quhuan and Zhang Fanghong(Gansu Academy of Medical Sciences,Lanzhou 730050;1Lanzhou Taibao Pharmaceutical Co.Ltd.)

【机构】 甘肃省医学科学研究院

【摘要】 目的优选安乳颗粒中丹参的提取工艺。方法以丹参酮ⅡA的含量为考察指标,应用L9(34)正交试验法考察乙醇浓度、液料比、提取时间对提取效果的影响。结果影响因素依次是:乙醇浓度(A)>液料比(B)>提取时间(C),最佳制备工艺为A2B2C2,即加8倍量80%乙醇,加热回流提取2次,每次1.5h。结论该优选制备工艺合理,有效成分提出率高。

【Abstract】 Objective To optimize the extracting procedure of Salvia miltiorrhiza in Anru keli.Methods TanshioneⅡA as a detective target,the optimum extracting conditions were studied by the orthogonal test of L9(34).The experiment was involved three factors: alcohol concentration(A),liquid-solid ratio(B),extracting time(C).Results The influencing effect of factors was as follows A>B>C.The optimizing preparation conditions were A2B2C2,that was 8 times 80% alcohol was added,and extracted 1.5h for two times.Conclusion The optimum preparation procedure is reliable and the extracting rate of active component is high.

【基金】 甘肃省重大研发项目(编号GKS002-01-14);甘肃省重点中医药科研项目(编号GZK-2009-11)
  • 【文献出处】 中国药事 ,Chinese Pharmaceutical Affairs , 编辑部邮箱 ,2010年08期
  • 【分类号】R286
  • 【被引频次】4
  • 【下载频次】65
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