【摘要】 法呢醇X受体(FXR)通过调节胆汁酸的合成、分泌和吸收来调节胆汁酸的代谢和稳态。法呢醇X受体激动剂有望成为治疗胆汁酸代谢相关疾病的新型药物。该文对近年来报道的法呢醇X受体激动剂进行简要综述。更多还原

【Abstract】 Farnesoid X receptor(FXR),a key controller of bile acid homeostasis and metabolism,regulates bile acid synthesis,secretion,and absorption.FXR agonists are expected to be new kind of therapeutic drugs for diseases related to bile acid metabolism.The progress on the research of FXR agonists in recent years was summarized.更多还原