节点文献
重症患者阵发心房颤动伴快速心室率的治疗方法研究
Treatment of Paroxysmal Atrial Fibrillation with Rapid Ventricular Rhythm in Critically Ill Patients
【摘要】 目的:观察病因治疗能否使重症监护病房中阵发心房颤动(简称房颤)患者转复窦律;比较静脉注射毛花苷丙-胺碘酮序贯治疗与单独注射胺碘酮转复无心脏病基础的房颤效果。方法:42例发作阵发性房颤伴快速心室率的危重症患者进行病因治疗,对未纠律者随机分配至毛花苷丙-胺碘酮序贯治疗与单独胺碘酮治疗组。结果:病因治疗后23例患者转复窦律。余19例患者进行随机分组,2组胺碘酮用量差异无统计学意义(P=0.386),心率变化差异无统计学意义(P=0.974),复发率差异无统计学意义(P=0.85)。结论:病因治疗可转复危重症患者房颤心律。对病因治疗不能纠律者,直接静脉注射胺碘酮效果与毛花苷丙-胺碘酮序贯治疗相同。
【Abstract】 OBJECTIVE:To observe effect of etiological treatments on revival of sinus rate in patients with paroxysmal atrial fibrillation and to compare the effect of cedilanid-amiodarone with amiodarone alone with intravenous administration on atrial fibrillation without heart disease history.METHODS:42 critically ill patients with paroxysmal atrial fibrillation were treated with etiological therapy.Patients without revival of sinus rhythm were randomly assigned to be treated with cedilanid-amiodarone or amiodarone alone.RESULTS:After etiological therapy,sinus rhythm of 23 patients was revived and other 19 patients were randomly grouped.No statistically significance was noted in difference of amiodarone dosages(P=0.386),change of heart rate(P=0.974) and recurrence rate(P=0.85) between two groups.CONCLUSION:Etiological therapy could restore sinus rhythm in patients with paroxysmal atrial fibrillation.The effecicacy of venous injection of amiodarone in patients without revival of sinus rhythm is similar to cedilanid-amiodarone sequence therapy.
【Key words】 Paroxysmal atrial fibrillation; Etiological treatment; Amiodarone; Cedilanid; Intensive care;
- 【文献出处】 中国药房 ,China Pharmacy , 编辑部邮箱 ,2010年30期
- 【分类号】R459.7;R541.75
- 【下载频次】58