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中药退黄外洗液质量标准研究
Quality Standard of Jaundice-abating Chinese Herbal Lotion for External Use
【摘要】 目的:建立中药退黄外洗液的质量标准。方法:采用薄层色谱(TLC)法对方中大黄、薄荷脑进行定性鉴别;采用高效液相色谱(HPLC)法对制剂中栀子苷进行含量测定。结果:TLC斑点清晰,分离度好、专属性强。栀子苷进样浓度在5.46~81.9μg.mL-1范围内与峰面积积分值呈良好线性关系(r=0.9998);平均回收率为98.38%,RSD=1.53%(n=6)。结论:所建标准可用于中药退黄外洗液的质量控制。
【Abstract】 OBJECTIVE:To establish the quality standard of Jaundice-abating Chinese herbal lotion for external use. METHODS:The component Rheum officinale and menthol were qualitatively identified by TLC,and the content of jasminoidin in formulation was determined by HPLC. RESULTS:The TLC spots were clear,well-separated and specific. The linear range of jasminoidin was 5.46~81.9μg·mL-1(r=0.999 8) with an average recovery of 98.38%(RSD=1.53%,n=6). CONCLUSION:Established quality standard can be used for the quality control of Jaundice-abating Chinese herbal lotion for external use
【Key words】 Jaundice-abating Chinese herbal lotion for external use; Quality standard; TLC; HPLC;
- 【文献出处】 中国药房 ,China Pharmacy , 编辑部邮箱 ,2010年15期
- 【分类号】R286
- 【被引频次】4
- 【下载频次】128