【摘要】 目的:提高门诊抗菌药物注射剂应用的安全性。方法:采用前瞻性随机对照方法,选取我院门诊2007年应用抗菌药物注射剂的患者为研究对象,随机分为对照组与干预组,针对联合用药因素,采用宣传教育、行政干预、监督检查等措施进行临床干预,观察干预前、后的联合用药合理性、不良反应发生率等变化情况。结果:与对照组相比,干预组联合用药合理性明显提高(P<0.01),干预后不良反应发生率降低。结论:针对联合用药因素进行干预,可提高门诊抗菌药物注射剂应用的安全性。更多还原

【Abstract】 OBJECTIVE:To improve the safety of antibiotic injections in outpatient department. METHODS:In a prospective randomized control study,outpatients treated with antibiotic injections in 2007 were chosen to be the subjects. The subjects were randomized into control group and intervention group. Education,administration intervention and inspection were adopted in clinical intervention considering the factor of drug combination. The rationality of drug combination and the incidence of ADR before and after intervention were observed. RESULTS:As compared with control group,the rationality of drug combination in intervention group was improved obviously(P<0.01) and the incidence of ADR after intervention decreased. CONCLUSION:The safety of antibiotic injections in outpatient department is improved by intervention to drug combination.更多还原