【摘要】 目的:了解尼古丁药贴对慢性阻塞性肺疾病与肺心病患者的戒烟效果。方法:将412位吸烟者随机分为3组:尼古丁药贴组(药贴组)138人,卫生宣教组(宣教组)135人及对照组139人。药贴组按处方用药,12周;宣教组每2周访视1次,宣传、规劝戒烟,12周;对照组不予干预。结果:12周戒烟率药贴组、宣教组及对照组分别为60.9%、8.9%和5.8%,6个月后的戒烟率分别为40.6%、11.1%和5.8%。药贴组12周及6个月戒烟率均明显好于宣教组和对照组,差异均有统计学意义(P<0.001)。药贴组中有23人因不能坚持戒烟而退出;19人有皮肤过敏、恶心、呕吐等反应,其中6人仍达到了即刻戒烟。结论:尼古丁药贴是帮助烟民戒烟的有效方法,而宣传教育是基础,也有一定的戒烟效果。更多还原

【Abstract】 Objective:To observe the efficacy of nicodinell on smoking cessation in patients with chronic obstructive pulmonary disease and cor-pulmonale.Methods: The smokers were randomly divided into three groups: Nicotinell group,n=138,the subjects were patched for ni-cotinell on their skin for 3 months according to the prescription;Health education group,n=135,smokers received the education every two weeks for a total of 3 months;and Control group,n=139,no intervention was conducted.Results: For 3 months of time,the smoking cessation rates in Nicotinell group,Education group and Control group were 60.9%,8.9% and 5.8% respectively.At 6 months of time,the cessation rates were 40.6%,11.1% and 5.8% respectively.The cessation rate of Nicotinell group was significantly higher than the other two groups(P<0.01),and there was no statistical diffe-rence between the Education group and Control group.In Nicotinell group,there were 23 smokers withdrew from the program,19 smokers suffered from nausea,vomiting,dermal allergy,even though,6 of them persisted to quit smoking successfully.Conclusions: The nicontinell intervention presented the effective promotion for stopping smoke,whereas the health education was necessary and it played an important role as well.更多还原