【摘要】 目的:研究急性ST段抬高型心肌梗死(STEMI),患者PCI术前后合并抑郁对手术前后生存质量的影响。方法:连续抽样收集两家三甲医院确诊的STEMI患者,以BDI《BECK抑郁自评问卷》进行情绪评测,并进行随机对照研究,其中抑郁组72例,非抑郁组137例;对照组35例为冠状动脉造影正常患者。在入选当时和术后3个月各进行1次随访,以《健康状况问卷-简表36》进行生存质量评判。应用SPSS13.0统计软件进行统计分析。结果:随访3个月,STEMI患者PCI术后抑郁组全部生活质量评分均显著低于非抑郁组(P<0.05);抑郁评分与患者生存质量评分显著负相关(P<0.05)。结论:STEMI患者PCI术前后合并明显的心理障碍,使患者生存质量明显降低。更多还原

【Abstract】 Objective:To study mental disorders in patients with STEMI undergoing percutaneous coronary intervention and investigated a correlation between depression and health related quality of life.Methods:Sampled randomly patients with STEMI in two general hospitals and built a case-control study at the same time.BDI was used to investigate mental disorders in the patients.The study group consisted of 209 patients with STEMI treated with primary PCI, which were divided into two groups:group A-137 persistently nondepressed patients, group B-72 patients with depression, including 31 persistently depressed patients and 41 remittent depressed patients.The control group consisted of 35 healthy subjects .With SF-36,the impact of depression on quality of life of STEMI patients treated with primary PCI was evaluated.Questionnaires were used to investigate the subjects’ quality of life before PCI and 3 months’ after PCI.All data was analyzed with SPSS 13.0 statistical software.P <0.05 was considered statistically significant.Results:After 3 months’ following assessment, STEMI patients with depression had worse quality of life than the patients without depression (P<0.05).There was a negative correlation between grades of depression and the quality of life (P<0.05).Conclusion:Depression which induce a poor quality of life are found significantly in patients with STEMI treated with primary PCI.It is important to diagnosis mental disorders and treat them in time.更多还原