【摘要】 目的:探讨间苯三酚与氧化亚氮(笑气)联合,应用于产程中的作用。方法:正常单胎足月初产妇400例,将其随机分为间苯三酚联合氧化亚氮组(观察组)、单用间苯三酚组(对照组1)、单用氧化亚氮组(对照组2)和不用药物组(对照组3),各100例。分析观察组与对照组(3组)的镇痛效果、产程时间、宫颈扩展速度、分娩方式、产后24h出血量及新生儿评分的情况。结果:观察组与对照组比较,镇痛效果更好,第一、二产程及总产程时间明显缩短,差异有统计学意义(P<0.05)。观察组用药后宫口扩张最大速度为3.80cm/h,对照1、2、3组分别为2.60、2.30、2.10cm/h,观察组与对照组比较,差异有统计学意义(P<0.05)。观察组比对照组剖宫产率低,产后24h的总出血量少,差异有统计学意义(P<0.05);顺产率高,差异有统计学意义(P<0.05);阴道助产率差异无统计学意义(P>0.05)。新生儿出生后体重及Apgar评分差异无统计学意义(P>0.05)。结论:间苯三酚联合氧化亚氮有更好的分娩镇痛效果,可缩短产程,降低剖宫产率,减少产后出血量,对产妇及新生儿无不良影响,值得临床推广使用。更多还原

【Abstract】 Objective:To discuss the function of phloroglucine and the nitrous oxide (laughing gas) applies jointly in the course of childbirth. Methods:Normal single embryo full-term first birth women 400 cases,and be stochastically divided into the phloroglucine union nitrous oxide group (observation group),simply used the phloroglucine group (control group 1),simply used the nitrous oxide group(control group 2) and no used drugs for the control group 3,every group for 100 cases. Analysed the analgesic effects of observation group and control group (3 groups),the course of childbirth time,the cervix of the uterus rate of expansion,the childbirth way,post-natal 24 h leave the situation which the volume of blood,and the newborn grades. Results:The analgesic effects of the observation group was better than that of the control group,the first ,second and total course of childbirth time reduced obviously,the difference had unusual significance (P<0.05). The observation group applied drugs the harem mouth expansion average velocity was 3.80 cm/h,control group’s speed respectively was 2.60,2.30,2.10 cm/h,and the difference were significant (P<0.05). The observation group c-section rate was low,post-natal 24 h always leaved the volume of blood to be few,the difference was unusual significant (P<0.05); the production rate was high,the difference was significant (P<0.05); the vagina midwifery rate did not have the significant difference(P>0.05). Newborns were born the postosome to be heavy and the Apgar grading difference did not have significance (P>0.05). Conclusion:The phloroglucine union nitrous oxide has the better childbirth analgesic effect,may reduce the course of childbirth,reduces the rate of cesarean section,reduces the post-natal volume of blood,to the parturient woman and the newborn has no adverse effects,is worth promoting to use.更多还原