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利用动态血糖监测系统观察妊娠糖尿病患者孕中晚期的血糖漂移

The glycemic excursions at CGMS in gestational diabetes mellitus patients during the late second or early third trimester of pregnancy

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【作者】 吴静薛耀明李晨钟沈洁余艳红

【Author】 WU Jing,XUE Yao-ming,LI Chen-zhong,et al.Endocrinology Department of Nanfang Hospital of Nanfang Medical University ,Guangzhou 510515 ,China

【机构】 南方医科大学南方医院内分泌代谢科南方医科大学南方医院妇产科

【摘要】 目的利用动态血糖监测系统(CGMS)评估妊娠糖尿病(GDM)患者孕中晚期整体血糖漂移趋势。方法受检孕妇分为50g葡萄糖负荷试验(GCT)正常组、异常组及妊娠糖尿病(GDM)组,连续72h进行血糖监测。结果 GDM组整体血糖漂移幅度、三餐前后血糖升高速度及幅度、低血糖及高血糖事件发生次数均明显高于其他两组(P均<0.05)。结论 CGMS能够准确反映出GDM患者的完整血糖变化,可增强患者对饮食控制、运动疗法、胰岛素治疗的依从性,对改善母婴结局具有重要意义。

【Abstract】 Objective To observe glycemic excursions in gestational diabetes mellitus (GDM) patients using the continuous glucose monitoring system (CGMS).Methods Forty pregnant women underwent a 1h 50g glucose challenge test (GCT) and a 3h 100g oral glucose tolerance test (OGTT).They were divided into three groups:normal GCT group (n=10),abnormal GCT group (n=10) and GDM group (n = 20).All subjects receiving the CGMS test were evaluated for glycemic excursion.Results The overall extent of glycemic excursions,apeed and extent of preprandial and postprandial blood glucose increment,and incidents of hypoglycemic and hyperglycaemic events were significantly higher in GDM group than in other two groups(all P<0.05).Conclusions CGMS can show the glycemic excursions in GDM,and contribute to the decision of diet treatment,exercise or drug treatment in pregnancy.

  • 【文献出处】 中国糖尿病杂志 ,Chinese Journal of Diabetes , 编辑部邮箱 ,2010年06期
  • 【分类号】R714.256
  • 【被引频次】33
  • 【下载频次】98
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