血浆脑钠肽水平与慢性左心衰患者心功能远期预后的关系

【摘要】 目的:脑钠肽(BNP)是主要由心室分泌的一种多肽类激素,其对慢性左心衰患者心功能远期预后评估的价值尚未确定,本研究旨在探讨脑钠肽对慢性左心衰患者心功能远期预后的预测价值。方法:选择2005年1月～2006年1月以"慢性左心衰"收住入院的患者80例,经住院治疗后心功能改善,临床症状好转出院,随访1年,随访率100%。比较两组不同BNP水平变化患者的远期随访结果。结果:高浓度BNP心衰患者较低浓度BNP心衰患者的远期死亡率高,两者有显著性差异(P<0.005)。结论:脑钠肽对慢性左心衰患者心功能远期预后有极高的预测价值。更多还原

【Abstract】 Objective:Brain natriuretic peptide(BNP) secreted mainly by the ventricles of a peptide hormone,the value of assessment of long-term prognosis in patients with chronic left heart failu has not been established,this study aimed to explore the brain natriuretic peptide on cardiac function in patients with chronic left heart failure long-term prognosis of the predictive value.Methods:Choose our hospital 80 cases of patients with chronic left heart failure in January 2005～January 2006,the cardiac function improved after hospitalization,clinical symptoms improved and discharged,1 year follow-up,Follow-up rate 100%.Compare two different sets of changes in BNP levels in patients with long-term follow-up results.Results:High concentrations of BNP in patients with heart failure have more long-term mortality rates than low concentration of BNP in patients with heart failure,there is a significant difference between the two sets(P<0.005).Conclusion:Brain natriuretic peptide has a high predictive value on long-term prognosis of cardiac function in patients with chronic left heart failure.更多还原