【摘要】 目的对住院患者内镜下逆行胰胆管造影后胰腺炎(PEP)进行回顾性研究,分析PEP的危险因素,提出适合实际情况的预防措施。方法 2006年1月～2007年12月,该院住院行内镜下逆行胰胆管造影(ER-CP)305次。以PEP为因变量,以16个患者因素、17个医源因素为自变量进行统计分析,并行Logistic回归多因素分析,找出PEP的独立危险因素。结果 305次患者中,51次发生PEP(16.7%)。单因素分析显示,胰管显影与PEP密切相关。结论胰管显影是PEP的危险因素,术前使用胰酶抑制剂不能降低PEP风险。更多还原

【Abstract】 [Objective]The aim of this study is to analyze the risk factors for post-ERCP pancreatitis in our cases and find measures of prevention. [Methods]Data of consecutive 305 patients, who have undergone ERCP at Peking University Third Hospital from January 2006 to December 2007, were enrolled in the study to analyze the in-hospital morbidity. Dependent variable was in-hospital morbidity, whereas the independent variables included 16 patient-related and 17 procedure-related risk factors. Logistic regression analysis was used to find the risk factors for PEP. [Results]In 305 patients, morbidity rate of PEP was 16.7% . PEP was associated with the risk of pancreatic duct imaging.[Conclusions]Pancreatic duct injection is the risk factor of PEP. Trypsin inhibitor can not be used before surgery to reduce the risk of PEP.更多还原