【摘要】 目的:为临床医师全面了解奈西立肽的药理学特性,促进该药在临床更好的应用。方法:综合近几年来国内、外文献,综述奈西立肽药理学特性及其临床应用新动向。结果:奈西立肽对于失代偿期心衰的治疗,特别是在急性心肌梗死并发心力衰竭、心力衰竭伴肾衰竭、心力衰竭伴肺动脉高压症时的应用,取得满意的疗效。结论:奈西立肽是治疗心力衰竭的一线药物,研究进展较快,有很好的应用前景。更多还原

【Abstract】 OBJECTIVE:To facilitate clinicians thorough understanding of the pharmacological characteristics of rhBNP(Lyophiluzed Recombinant Human Brain Natriuretic Peptide) and promote its clinical application.METHODS:The pharmacological characteristics and new clinical application of nesiritide were reviewed through a meta-analysis of domestic and foreign documents about this medicine.RESULTS:Nesiritide has satisfying effects in treating decompensated heart failure,especially for acute myocardial infarction accompanied by heart failure,heart failure accompanied by renal failure,and heart failure accompanied by pulmonary hypertension.CONCLUSION:Nesiritide is the first line therapy for heart failure.The research on Nesiritide has achieved a rapid progress and its clinical application hold an optimistic outlook.更多还原