【摘要】 目的测定礞石滚痰片中黄芩苷的含量。方法采用高效液相色谱(HPLC)法。色谱柱为DiamonsilTM(钻石)C18柱(250mm×4.6mm,5μm),以甲醇-0.2%磷酸溶液(47:53)为流动相,检测波长为280nm。结果黄芩苷进样量在0.184～2.760μg范围内与峰面积线性关系良好,平均加样回收率为98.52%,RSD为0.47%(n=6)。结论 HPLC法快速、准确,可用于该制剂的质量控制。更多还原

【Abstract】 Objective To determine the contents of baicalin in Mengshi Guntan Tablets.Methods The HPLC method was adopted and the DiamonsilTM C18 column(250 mm×4.6 mm,5 μm) was used.The mobile phase was methanol-0.2%phosphoric acid(47:53).The detection wavelength was at 280 nm.Results The calibration curve of baicalin was linear in the range of 0.184-2.760 μg,the average recovery rate was 98.52%,RSD=0.47%(n=6).Conclusion HPLC is quick and accurate,which can be used for the quality control of Mengshi Guntan Tablet.更多还原