【摘要】 本文对降糖药吡格列酮的合成方法进行了归纳整理,对其操作步骤和特点作了概括总结,并分析了每种合成方法的特点,提出了汇聚式的合成路线是适合工业化的绿色环保工艺,可根据具体生产的实际情况选择适当方法。更多还原

【Abstract】 A systematically review of the synthesis methods of Pioglitazone are summarized in this paper.The basic manipulation procedures are illustrated for each of the ten synthetic routes.Evaluation and comparison are also discussed for the further development of the industrial process.更多还原