【摘要】 目的:了解近年来基层医院在非感染性发热性疾病对抗菌药物的应用状况。方法:回顾性调查某二级医院2007～2008年除外感染明确的内科和外科发热性病例560例,调查每例发热患者及相关辅助检查,出院诊断和抗菌药物使用情况。结果:本组560例非感染性发热性疾病患者治疗中未使用抗菌药物治疗者219例(39.11%),使用抗菌药物者341例(60.89%)。560例中体温≥40℃者共145例,全部使用了抗菌药物(100.00%),涉及使用的抗菌药物共6大类13个品种,使用最多的是头孢菌素,以第三代头孢菌素为主,其他依次为喹诺酮类抗菌素、克林霉素及林可霉素、抗结核药、氨基糖苷类抗菌素和美他环素。结论:该基层医院对非抗染性发热性疾病抗生素的不合理使用情况较为突出,建议仍需进一步加强对基层医院医务人员抗菌素药物合理使用的教育、宣传与管理工作,以防止细菌耐药性的产生。更多还原

【Abstract】 Objective:To learn about the application of antimicrobial agents in non-infectious febrile diseases in the grass-roots hospitals in recent years. Methods:We had a retrospective survey of 650 fever cases except for clear medical and surgical cases and to investigate all the fever patents and their related examinations the discharge diagnosis and the use of antibacterial drugs in a second-class hospital from 2007 to 2008. Results:In the 560 patients,suffering from noninfectious febril disease 219 cases(39.11%) were not given antimicrobial agents and 341 cases(60.89%) were given antimicrobial agents in the treatment. 145 patients whose body temperature ≥40℃ in 560 cases were all given antimicrobial agents(100.00%) . The used antimicrobial agents,in total had 13 varieties of six categories,cephalosporins,mainly the third generation cephalosporins was used most frequently. Others antibiotics were quinolones,clindamycin and lincomycin,anti-tuberculosis drugs,amino sugar glycosides antibiotics and the united he cyclophilin. Conclusion:In the primary hospital the irrational use of antibiotics for non-anti-infectious febrile disease is more prominent,recommendations in order to prevent the emergence of bacterial resistance,the education,publicity and managerment of the rational use of antibiotic drugs is still needed to further strengthen in the primary hospital medical staff.更多还原