【摘要】 目的:探讨中期妊娠合并重型系统性红斑狼疮(systemic lupus erythematosus,SLE)患者终止妊娠的指征和处理方法。方法:对10例中期妊娠合并重型SLE行治疗性引产患者的临床资料进行回顾性分析。结果:4例患者妊娠前已确诊为SLE,6例妊娠后诊断为SLE。并发肾功能损害7例,肝功能损害1例,血液系统受损(进行性贫血、血小板减少)1例,呼吸系统受损1例,严重高血压1例。水囊引产6例,依沙吖啶羊膜腔内注射引产4例。无一例发生继发感染、产后出血、多器官功能衰竭。结论:妊娠期出现SLE病情活动及进行性重要脏器功能损害应及时终止妊娠。终止妊娠前后应积极治疗SLE,保护脏器功能。更多还原

【Abstract】 Objective:To evaluate the indications and treatment in labor induction of severe SLE second trimester pregnancy.Methods:10 cases of patients with labor induction of severe SLE second trimester were retrospectively analyzed.Results:4 cases were diagnosed as SLE before pregnancy,and 6 cases after pregnancy.There were 7 patients with kidney damage,1 with liver damage,1 with blood system damage,1 with respiratory system damage,and 1 case with heavy high blood pressure.6 cases were induced by water bag and 4 cases by ethacridine intra-amniotic injection.No case with infection,post-partum hemorrhage and multiple organ failure.Conclusion:Pregnancy should be terminated timely when SLE occurs and major organs are damaged.SLE should be treated actively before and after the termination for protection of organ functions.更多还原