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47例真菌性角膜溃疡临床分析

A Retrospective Study of 47 Mycotic Corneal Ulcer Cases

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【作者】 杨波童渝眉周卫亚

【Author】 YANG Bo,TONG Yu-mei,ZHOU Wei-ya(Chengdu No.7 People’s Hospital,Sichuan Chengdu 610021,China)

【机构】 成都市第七人民医院

【摘要】 目的:回顾性分析真菌性角膜溃疡的药物治疗临床经过,以探讨最佳治疗效果。方法:本组47例47眼全部行角膜刮片查见真菌菌丝、孢子确诊。对轻、中症病例行角膜病灶清创,结膜下注射0.2%氟康唑0.5 mL,频点0.2%氟康唑眼液和0.25%二性霉素B眼液抗真菌,全程散瞳治疗。重症患者配合每日静滴0.2%氟康唑注射液治疗。结果:47例经药物治疗,治愈38例,无效9例。结论:早期诊断、及时合理治疗是治愈真菌性角膜溃疡的关键。

【Abstract】 Objective:To evaluate the therapeutic efficient in 47 mycotic corneal ulcer cases with a retrospective study.Methods:47 out-patients with mycotic corneal ulcer underwent corneal scraping were examined with a microscope and confirmmed mycelium or spore.The mild and moderate cases were treated with debridement on the focus of corneal,and injected in subconjunctiva with 0.2% fluconazol 0.5ml,then followed by frequent 0.2% fluconazol and 0.25% amphotericin B eye drops,in combination with iridodilation all the course.The severe cases were treated by 0.2% fluconazol intravenously daily.Results:Among 47 cases,38 cases wee fully healed,9 cases did not have expected results.Conclusion:Mycotic corneal ulcer is one of the leading causes of blindness.Early diagnosis with early reasonable therapeutic intervention are the key to healing.

【关键词】 真菌角膜溃疡抗真菌药物
【Key words】 mycoticcorneal ulcerantifungal
  • 【文献出处】 现代临床医学 ,Journal of Modern Clinical Medicine , 编辑部邮箱 ,2010年06期
  • 【分类号】R772.21
  • 【下载频次】35
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