【摘要】 目的确定细菌性阴道病(bacterial vaginosis,BV)在妊娠妇女中的发病情况及对妊娠不良结局的影响。方法对来我院产科门诊行首次产前检查的孕妇2931例常规进行BV检测,所检测出的BV阳性孕妇自由选择是否进行治疗及治疗用药的方式,同意治疗者给予甲硝唑或克林霉素口服给药或甲硝唑阴道给药治疗。研究对象分为3组,BV阳性同意治疗并治疗有效者164例作为观察组1,BV阳性不同意治疗者及治疗无效者共98例作为观察组2,取BV阳性者相邻的BV阴性正常孕妇262例作为对照组。3组孕妇记录临产孕周、胎膜破裂时间、分娩情况及新生儿情况,分娩后取胎膜组织送病理检查并记录病理结果及进行产褥期随访。结果妊娠期BV的检出率为11.2%,观察组1与观察组2比较,早产、未足月胎膜早破及产褥感染发生率明显降低,差异有统计学意义(P<0.05);观察组2与对照组比较,早产、未足月胎膜早破、产褥感染及新生儿感染发生率均明显升高,差异有非常显著统计学意义(P<0.01)。结论妊娠期BV的检出率较高,可明显增加早产、未足月胎膜早破、产褥感染、新生儿感染等不良妊娠结局的发生率,BV阳性者经治疗后其不良妊娠结局的发生率明显降低,故对妊娠期BV进行常规筛查及系统的治疗有着非常重要的意义。更多还原

【Abstract】 Objective Todetermine the bacterial vaginosis(BV)in pregnant women and the incidence ofadverse pregnancy outcome.Methods The obstetric hospital to my first antenatal clinic visit in 2931 cases of pregnant women for BV conventional detection,the detection of BV-positive pregnant women freely choose whether or not to drug treatment and treatment of the way,consent to treatment given metronidazole or oral administration of clindamycin or metronidazole vaginal treatment.Subjects were divided into 3 groups,BV positive consent to treatment and treatment of 164 cases of force as the observation group 1,BV-positive do not agree to treatment and treatment of null and void as a total of 98 cases of observation group 2,check adjacent BV positive pregnant women BV-negative 262 cases as control group.Record Group 3 pregnant women in labor gestational age,fetal membrane rupture time,maternity and newborn,the fetal membranes after delivery check sent to pathological examination and record the pathological findings and follow-up to the puerperium.Results Gestational BV of 11.2 percent detection rate,the observation group 1 and 2 compare the observation group,prematurity,preterm premature rupture of membranes and puerperal infection were significantly lower,the difference has statistical significance(P<0.05);Observer Group 2 compared with the control group,prematurity,preterm premature rupture of membranes,puerperal infection and the incidence of neonatal infection rates were significantly higher,the difference has statistical significance(P<0.05 or 0.01).Conclusion The detection of BV in pregnancy rates are relatively high,can be a marked increase in premature labor,preterm premature rupture of membranes,puerperal infection,neonatal infection and other adverse pregnancy outcomes incidence,BV-positive after treatment of its adverse pregnancy outcomes significantly reduced the incidence of,so during pregnancy routine BV screening and treatment system has an important significance.更多还原