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超早期无创正压通气治疗重症急性胰腺炎所致肺损伤疗效观察

The Effect of Clinical Applications on Early Noninvasive Positive-pressure Ventilation in Severe Acute Pancreatitis with Acute Lung Injury

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【作者】 彭加英李先全范红英

【Author】 PENG Jiaying,LI Xianquan,FAN Hongying.Department of ICU,the Third Hospital of Mianyang,Sichuan Province 621000

【机构】 四川省绵阳市第三人民医院ICU

【摘要】 目的:评价超早期无创正压机械通气在治疗重症急性胰腺炎所致急性肺损伤患者的疗效。方法:对我科2006年3月-2009年6月收治的28例确诊重症急性胰腺炎所致急性肺损伤患者在常规治疗的同时,超早期辅以无创机械通气,同时记录患者血气分析、氧合指数、APACHE Ⅱ评分等资料。结果:2例死亡,24例成功脱机,氧合指数上升,APACHE Ⅱ评分下降,2例行无创通气3d后改为经口气管插管。结论:无创正压通气较有创正压通气更易早期实施,能在早期改善患者低氧血症以及由低氧血症带来的一系列损害,减少多器官功能障碍发生,适合临床推广。

【Abstract】 Objective: To explore the therapeutic effects of early noninvasive positive-pressure ventilation in severe acute pancreatitis(SAP)with acute lung injury(ALI).Methods:From March 2006 to June 2009,twenty-eight patients with SAP and ALI were treated by routine project and early noninvasive positive pressure ventilation.During the therapy,blood gas analysis,PaO2/FiO2 and APACHE Ⅱ score were registered.Results:Two cases died,twenty-four cases were evacuated ventilator successful,PaO2/FiO2 were raised,APACHE Ⅱ score was decline.Two cases were treated by endotracheal intubation instead three days later after noninvasive positive-pressure ventilation.Conclusion:Noninvasive positive-pressure ventilation provide airway positive pressure ventilation and without tracheal intubation or cut,which is early and easy to implement,can improve the hypoxemia and the series of damages.

  • 【文献出处】 医学理论与实践 ,The Journal of Medical Theory and Practice , 编辑部邮箱 ,2010年05期
  • 【分类号】R576;R563.8
  • 【被引频次】5
  • 【下载频次】49
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