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急性脑梗死患者血清同型半胱氨酸和超敏C反应蛋白检测的临床意义

Clinical significance of changes of serum homocysteine and High-sensitivity C-reactive protein levels in patients with acute cerebral infarction

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【作者】 李慧王蓓徐蓓

【Author】 LI Hui,WANG Pei,XU Pei.The First PeoPle’ s Hospital of Lianyungang,Lianyungang 222002,China

【机构】 江苏省连云港市第一人民医院

【摘要】 目的探讨急性脑梗死患者血清同型半胱氨酸(Hcy)和超敏C反应蛋白(hs-CRP)水平的变化及临床意义。方法应用EliSA法和免疫比浊法对36例急性脑梗死患者进行血清Hcy和hs-CRP水平测定,并与35名正常健康人作比较。结果急性脑梗死患者血清Hcy和hs-CRP水平均非常显著地高于正常人组(P<0.01),且血清Hcy水平与hs-CRP水平呈正相关(r=0.5872,P<0.01)。结论急性脑梗死患者血清Hcy和hs-CRP水平的升高与脑梗死的严重程度呈正相关,可作为预测急性脑梗死发生发展的敏感指标。

【Abstract】 Objective To explore the clinical significance of changes of serum Hcy and hs-CRP levels in the patients with acute cerebral infarction(ACI).Methods Hcy(with EliSA),hs-CRP(with immunoturbidimetry) levels were measured in 36 patients with acute cerebral infarction as well as in 35 contrals.Results The levels of serum Hcy and hs-CRP in the patients with ACI were significantly higher than those in contrals(P<0.01).Serum Hcy levels were positively correlated to hs-CRP levels(r=0.5872,P<0.01).Conclusions The levels of Hcy,and hs-CRP are markedly increased in the patients with ACI,which are positively correlated to the severity of ACI and may be taken as the sensitive biochemical markers for predicting its development.

  • 【文献出处】 中国医疗前沿 ,National Medical Frontiers of China , 编辑部邮箱 ,2010年20期
  • 【分类号】R743.33
  • 【被引频次】3
  • 【下载频次】60
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