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急性脑梗死患者血清同型半胱氨酸和超敏C反应蛋白检测的临床意义
Clinical significance of changes of serum homocysteine and High-sensitivity C-reactive protein levels in patients with acute cerebral infarction
【摘要】 目的探讨急性脑梗死患者血清同型半胱氨酸(Hcy)和超敏C反应蛋白(hs-CRP)水平的变化及临床意义。方法应用EliSA法和免疫比浊法对36例急性脑梗死患者进行血清Hcy和hs-CRP水平测定,并与35名正常健康人作比较。结果急性脑梗死患者血清Hcy和hs-CRP水平均非常显著地高于正常人组(P<0.01),且血清Hcy水平与hs-CRP水平呈正相关(r=0.5872,P<0.01)。结论急性脑梗死患者血清Hcy和hs-CRP水平的升高与脑梗死的严重程度呈正相关,可作为预测急性脑梗死发生发展的敏感指标。
【Abstract】 Objective To explore the clinical significance of changes of serum Hcy and hs-CRP levels in the patients with acute cerebral infarction(ACI).Methods Hcy(with EliSA),hs-CRP(with immunoturbidimetry) levels were measured in 36 patients with acute cerebral infarction as well as in 35 contrals.Results The levels of serum Hcy and hs-CRP in the patients with ACI were significantly higher than those in contrals(P<0.01).Serum Hcy levels were positively correlated to hs-CRP levels(r=0.5872,P<0.01).Conclusions The levels of Hcy,and hs-CRP are markedly increased in the patients with ACI,which are positively correlated to the severity of ACI and may be taken as the sensitive biochemical markers for predicting its development.
【Key words】 Acute cerebral infarction(ACI); Homocysteine(Hcy); High-Sensitivity C-reactive protein(hs-CRP);
- 【文献出处】 中国医疗前沿 ,National Medical Frontiers of China , 编辑部邮箱 ,2010年20期
- 【分类号】R743.33
- 【被引频次】3
- 【下载频次】60