【摘要】 从物理吸附涂层、共价键连接和微载体控释等方面综述了肝素功能化生物材料的最新研究进展.大量研究表明这些肝素材料具有抗凝血和/或生长因子释放的功能,但未来的研究重点是构建各种控制释放肝素亲和性生长因子的系统.更多还原

【Abstract】 Ths recent progress in heparin-functionalization of biomaterials is reviewed.Achievements in materials preparation based on physical adsorption coatings,covalent graft and biomimetic microcarriers are included.All these heparin-containing materials have antithrombogenicity and/or can control the release of growth factors,which have been extensively investigated.However,the research in the near future will focus on construction of various systems to control the release of heparin affinitive growth factors.更多还原