【摘要】 目的利用高频超声探讨类风湿关节炎(RA)与亚临床型动脉粥样硬化病变之间的相关性。方法超声测量45例RA患者及25例正常对照组颈动脉内-中膜厚度(IMT)及肱动脉血流介导的血管舒张(FMD),并进行对比分析。结果 RA患者颈动脉IMT较正常对照组明显增厚(P<0.01);RA组FMD较正常对照组明显降低(P<0.01)。结论 RA与动脉粥样硬化的发生有明显相关性,高频超声可作为早期预测RA患者亚临床型动脉粥样硬化有效的、敏感且无创的手段。更多还原

【Abstract】 Objective To evaluate the correlation between subclinical atherosclerosis and rheumatoid arthritis (RA) by high-resolution ultrasonography.Methods Carotid artery intima-media thickness(IMTc) and brachial arterial flow-mediated dilation(FMD) were studied by ultrasound in 45 patients with RA and 25 normal controls.Results IMTc in patients with RA was thickness significantly than that of normal group(P < 0.01) .FMD of the brachial artery in patients with RA was low significantly than that of normal group(P < 0.01) .Conclusion Atherosclerosis is related to rheumatoid arthritis.High-resolution ultrasonography may be considered as a promising,sensitive and non-invasive tool for assessing subclinical atherosclerosis in RA patients in early stage.更多还原