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桃仁乙醇提取物对小鼠出血时间和凝血时间的影响

Effects of ethanol extract of the Semen persicae for bleeding time and coagulation time in mice

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【作者】 金松今张红英朴惠顺李兰

【Author】 JIN Song-jin1,ZHANG Hong-ying2,PIAO Hui-shun3,LI Lan(1.Department of Experimental Animal,Health Science Center;2.Teaching Center of Functional Experimental Science,College of Basic Medicine;3.Research Center,College of Pharmacy:Yanbian University,Yanji 133000,Jilin,China)

【机构】 延边大学医学部实验动物科延边大学基础医学院机能实验中心延边大学药学院药物研究中心延边大学医学部

【摘要】 [目的]探讨桃仁乙醇提取物对小鼠出血时间和凝血时间的影响.[方法]取小鼠随机分为对照组、桃仁乙醇提取物大、中、小(2.4,1.2,0.6g/kg)剂量组,分别给予相应药物,15d后采用玻片法、毛细玻管法及断尾法测定小鼠凝血时间及出血时间.[结果]桃仁乙醇提取物大、中剂量组小鼠出血时间和凝血时间均明显延长.[结论]桃仁乙醇提取物具有抗凝血作用.

【Abstract】 OBJECTIVE To study the effects of the ethanol extract of Semen persicae for bleeding time and coagulation time in mice.METHODS The mice were randomly divided into control group and large,middle and small dosages of ethanol extract of Semen persicae(2.4,1.2,0.6 g/kg)groups,and administrated with the extract for 15 days,and the bleeding time and coagulation time were detected by the methods of grass,capillary and cutting tail.RESULTS The bleeding time and coagulation time were more longer in the groups of large and middle dosages of ethanol extract of Semen persicae than in the control group.CONCLUSION The ethanol extract of Semen persicae has the effects of anti-coagulation.

  • 【文献出处】 延边大学医学学报 ,Journal of Medical Science Yanbian University , 编辑部邮箱 ,2010年02期
  • 【分类号】R285.5
  • 【被引频次】32
  • 【下载频次】592
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