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山羊奶配方奶粉预防婴幼儿牛奶过敏的临床研究

Clinical Study of Goat Milk Formula for the Prevention of Milk Allergy in Infants

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【作者】 陈怀玉赖雪辉李俊周蓓张小玲

【Author】 CHEN Huaiyu,LAI Xuehui,LI Jun,ZHOU Bei,ZHANG Xiaoling,et al(Department of Health Defence,the Chinese Medicine Hospital of Tianhe District,Guangzhou 510655,China)

【机构】 广东省广州市天河区中医医院卫防科

【摘要】 目的从临床学角度研究山羊奶配方奶粉预防婴幼儿牛奶过敏的效果。方法选择临床诊断为牛奶蛋白过敏的婴幼儿78例,用山羊奶配方奶粉替代牛奶配方奶粉对患者进行膳食治疗1~6个月,比较治疗前后过敏症状和实验室指标的变化。结果治疗后患儿过敏症状瘙痒、腹泻、便秘、腹痛等明显减少,过敏体征特应性皮炎明显改善,治疗时间越长过敏症状和特应性皮炎改善效果越好。治疗前后实验室检查43人,全血嗜酸细胞计数(EC)、血清总IgE(TIgE)、牛奶蛋白IgE(CMPIgE)有统计学差异(P<0.01),治疗时间越长统计学差异越明显(P<0.005)。结论山羊奶配方奶粉预防婴幼儿牛奶过敏是可行的。

【Abstract】 Objective To study the effects of goat milk formula for the prevention of milk allergy in infants from the perspective of clinic. Methods 78 infants with milk protein allergy selected by clinical diagnosis were treated with goat milk formula instead of milk formula for 1 to 6 months,the allergy symptoms and changes of laboratory indicators before and after treatment were compared. Results After treatment,the allergy symptoms of infants such as itching,diarrhea,constipation,abdominal pain,et al significantly decreased,the allergy sign such as atopic dermatitis significantly improved. The longer the treatment time,the better the improvement of allergy symptoms and atopic dermatitis. 43 cases were taken the laboratory tests before and after treatment,there were significant differences in EC,T IgE and CMP IgE(P <0.01) ,the longer the treatment time,the more significant the statistical differences(P <0.005) . Conclusion Goat milk formula for the prevention of milk allergy in infants is feasible.

【关键词】 山羊奶配方奶粉婴幼儿牛奶过敏
【Key words】 Goat milk formulaInfantsMilk allergy
【基金】 广州市天河区卫生系统科技项目(编号:06KW001)
  • 【文献出处】 临床医学工程 ,Clinical Medicine & Engineering , 编辑部邮箱 ,2010年10期
  • 【分类号】R174
  • 【被引频次】11
  • 【下载频次】318
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