【摘要】 以易得的5-硝基-2-氯苯腈为原料,经水合肼还原,采用改进的Schiemann反应氟化和碱性水解得到5-氟水杨酸,总收率达55.7%.更多还原

【Abstract】 5-fluorosalicylic acid was prepared from 2-chloro-benzonitrile by nitration,reduction with hydrazine hydrate,which was converted to 5-fluoro-2-chlorobenzonitrile through improved Schiemann reaction and then hydrolyzation with NaOH with an overall yield of 55.7 %.更多还原