【摘要】 目的优选乳痛宁颗粒的除杂工艺。方法分别采用高速离心法、乙醇沉淀法、吸附澄清技术,以水浸出物收率、总多糖保留率、芍药苷保留率及淫羊藿苷保留率为指标,通过与自然沉降法的对比,比较3种除杂工艺的差异。结果 3种除杂工艺对4个指标均有不同程度的影响,其中吸附澄清技术中加入4%药液量B组分和2%药液量A组分的正天成ZTC1+1-Ⅱ型天然澄清剂法,能使水浸出物收率降至16.5%,使总多糖、芍药苷、淫羊藿苷保留率分别为94.84%、96.51%、92.11%。结论吸附澄清技术中ZTC1+1-Ⅱ型天然澄清剂法可作为乳痛宁颗粒的除杂工艺。更多还原

【Abstract】 Objective To choose the best clarification process of Rongtongning Granule (Traditional Chinese Medicine).Methods By determinating dry extract percent,total polysaccharide content,paeonoside content and icariine content three clarification processes including high-speed centrifugal,ethanol precipitation,adsorption clarification technique were compared with nature sedimentation.Results Three clarification processes had different level effect on the four indexes.Among them,adsorption clarification technique with 4% B component and 2% A component of Zheng Tian Chen (Traditional Chinese Medicine,ZTC)-Ⅱ nature clarifying could reduce the dry extract percent to 16.5% or so and make the retention rate of the active components above 92% respectively.Conclusion In the adsorption clarification technique,ZTC-Ⅱ nature clarifying agent can be used as clarification process Rongtongning Granule.更多还原