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主动脉瓣钙化与冠心病有关联

Association between aortic valve calcification and coronary artery disease

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【作者】 龚东楼建英彭健张伟王达理钱维源

【Author】 GONG Dong1,LOU Jian-ying2,PENG Jian1,ZHANG Wei2,WANG Da-li2,QIAN Wei-yuan2(1.Department of Cardiology,Fifth Affiliated Hospital,Sun Yat-Sen University,Zhuhai 519000,Guangdong,China;2.Department of Cardiology,PLA 454 Hospital,Nanjing 210002,Jiangsu,China)

【机构】 中山大学附属第五医院心内二科解放军第四五四医院心内科

【摘要】 目的:探讨中国南方部分汉族人群主动脉瓣钙化与冠心病之间的关系。方法:选取同期行冠状动脉造影检查和超声心动图检查患者1 153例,探讨主动脉瓣钙化与冠心病的相关性。结果:冠心病组主动脉瓣钙化的检出率明显高于非冠心病组(32.6%vs.13.9%,P<0.01),多因素Logistic回归分析结果显示,除传统危险因素如年龄、性别、高脂血症、糖尿病外,主动脉瓣钙化也是全组冠心病的一项独立的预测因子(OR=1.53,P<0.05)。结论:主动脉瓣钙化与全组冠心病发病之间存在显著的相关性,是冠心病的一项有意义的独立预测因子。

【Abstract】 AIM: To determine the relationship between aortic valve calcification(AVC) and coronary artery disease(CAD) in part of the Han population in southern China.METHODS: Enrolled in the study were 1 153 subjects who underwent both transthoracic echocardiography(TTE) and coronary arteriography(CAG),and the relationship between aortic valve calcification(AVC) and CAD was explored.RESULTS: The prevalence of AVC was significantly higher in the CAD group compared with that in non-CAD group(32.6% vs.13.9%,P<0.01).Multiple logistic regression analysis showed that in addition to age,gender,diabetes mellitus and hyperlipidemia(all P<0.01),AVC(P<0.05) was an independent positive predictor of coronary arteriography.CONCLUSION: There is a significant association between the presence of AVC and CAD.Aortic valve calcification is an independent predictor of CAD.

  • 【文献出处】 心脏杂志 ,Chinese Heart Journal , 编辑部邮箱 ,2010年06期
  • 【分类号】R541.4
  • 【被引频次】1
  • 【下载频次】70
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