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采用光学相干断层成像技术评价国产雷帕霉素洗脱支架术内膜覆盖情况

Evaluation on neointimal coverage of domestic sirolimus eluting stent after implantation for nine months by Optical Coherence Tomography (OCT)

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【作者】 宋现涛杜梦阳陈欣苑飞周玉杰吕树铮陈韵岱

【Author】 SONG Xiantao,DU Mengyang,CHEN Xin,YUAN Fei,ZHOU Yujie,LU Shuzheng,CHEN Yundai Department of Cardiology,Capital Medical University affiliated Beijing Anzhen Hospital,Beijing Institute of Heart,Lung and Blood Vessel Diseases,Beijing 100029,China

【机构】 首都医科大学附属北京安贞医院北京市心肺血管疾病研究所心内科北京市心肺血管疾病研究所干部病房解放军总医院心内科

【Abstract】 Objective:Confirming complete neointimal coverage after implantation of drug-eluting stent(DES)is clinically important because incomplete stent coverage is maybe responsible for late thrombosis and sudden cardiac death.Optical coherence tomography(OCT)is a high-resolution(≈10 μm)imaging technique capable of detecting a thin layer of neointimal hyperplasia(NIH)inside DES.Helios stent system(KinheIy Bio-tech Co(Shenzhen).Ltd)is a new generation of sirolimus eluting stents.Methods:Motorized optical coherence tomographic pullback was performed at 9-month follow-up to examine consecutive Helios stent mplantations in 10 patients.NIH thickness inside each strut and NIH area percentage inside each cross-section were measured.Results:In total,2063 struts in 296 mm stented segments were analyzed.Overall,NIH thickness were(95.7±66.62)μm,rates of exposed struts was 60.2% and the average NIH area percentage was 5.0618% ± 5.6625%.Conclusion:Our study suggests that dual antiplatelet therapy after Helios stent implantation must be continued at least 9months after DES implantation.

【基金】 北京市科委高科技战略主题计划资助项目(D0906006040191);北京市科技新星计划资助项目(2007A001)
  • 【文献出处】 心肺血管病杂志 ,Journal of Cardiovascular and Pulmonary Diseases , 编辑部邮箱 ,2010年S1期
  • 【分类号】R543
  • 【被引频次】1
  • 【下载频次】107
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