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低分子肝素预防人工髋关节置换术后下肢深静脉血栓形成的临床观察

CLINICAL OBSERVATION OF LOW MOLECULAR WEIGHT HEPARIN FOR PREVENTION ON LOWER EXTREMITY DEEP VEIN THROMBOSIS AFTER HIP ARTHROPLASTY

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【作者】 贺葵王治张忠杰陈歌

【Author】 HE Kui,WANG Zhi,ZHANG Zhong-jie,et al.(Department of Orthopaedics,Affiliated Hospital of Luzhou Medical College,Luzhou 646000,China)

【机构】 泸州医学院附属医院骨与关节外科

【摘要】 [目的]探讨低分子肝素预防人工髋关节置换术后下肢深静脉血栓(DVT)形成的疗效与临床应用特点。[方法]对某院2008年5月~2009年7月共98例人工髋关节置换术进行回顾分析。病人分为两组,对照组52例采用常规预防措施加用阿司匹林;观察组46例采用常规预防措施加用低分子肝素。术后3~10d行下肢血管彩色多谱勒超声检查,以了解深静脉血栓发生的情况。[结果]对照组发生深静脉血栓8例,观察组发生深静脉血栓1例,两组比较χ2=5.11,P﹤0.05,差异有统计学意义。[结论]低分子肝素可有效降低人工髋关节置换术后下肢深静脉血栓形成。治疗时应给予积极的专科护理。

【Abstract】 [Objective] To discuss the curative effects and clinical application of low molecular weight heparin(LMWH)for prevention on lower extremity deep vein thrombosis after hip arthroplasty.[Methods] Retrospectively analysis was used for the total 98 patients with hip arthroplasty from May 2008 to July 2009 in Affiliated Hospital of Lu Zhou Medical College.The patients were randomly divided into two groups.The Control group(52cases)received the general preventive measures and As-pirin.The observation group(46 cases)received the general preventive measures and low molecular weight heparin.All the patients did color doppler ultrasonography to investigate the situation of deep vein thrombosis of lower extremity after hip arthroplasty for 3 to 10 days.[Results] 8 cases of deep vein thrombosis were found in the control group,and 1 cases of deep venous thrombosis were found in the observation group.There were significant differences between these group(χ2 = 5.11,P﹤0.05).[Conclusion] The incidence of deep venous thrombosis in lower extremity vascular can be effectively reduced by low molecular weight heparin after hip arthroplasty.Specific nursing should be actively given to the patients in this therapy.

  • 【文献出处】 现代预防医学 ,Modern Preventive Medicine , 编辑部邮箱 ,2010年18期
  • 【分类号】R687.4
  • 【被引频次】17
  • 【下载频次】179
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