【摘要】 [目的]分析恶性血液病并发侵袭性真菌感染(IFI)的临床特点,探讨有效地治疗方法。[方法]对患者的临床资料包括临床表现、致病菌、感染部位和疗效等进行分析。[结果]致病菌以念珠菌为主,感染部位以呼吸道感染为主;治疗总有效率为60%,氟康唑组有效率为37.5%,伊曲康唑组有效率为58.3%,卡泊芬净组有效率为70%。[结论]对恶性血液病并发侵袭性真菌感染可疑患者应及时进行经验性抗生素治疗,卡泊芬净抗菌谱广,对IFI的治疗效果好。更多还原

【Abstract】 [Objective] To analyze the clinical characteristics of the hematologic malignancies complicated by invasive fungal infections (IFI) and effective treatment methods. [Methods] The clinical data of patients including clinical performance, pathogenic bacteria, infection site and efficacy were analyzed. [Results] Candida was the main pathogenic bacteria; respiratory tract infection was the main infection site; the total effective rate was 60%, fluconazole group was 37.5%, itraconazole group was 58.3%, and Caspofungin group rate was 70%. [Conclusion] Patients of hematologic malignancies complicated by invasive fungal infections should be treated timely with empirical antibiotic treatment, and Caspofungin broad spectrum antibiotic has good effect on IFI.更多还原