【摘要】 目的:探讨缺血后适应处理在急性心肌梗死急诊经皮冠状动脉介入(PCI)术中对再灌注心律失常的作用及临床应用价值。方法:将56例ST段抬高型急性心肌梗死行急诊PCI的患者随机分为常规处理组(29例)和缺血后适应组(27例)。术中出现再灌注心律失常后常规处理组予以药物或临时起搏处理,缺血后适应组立即予以球囊低压扩张多次使罪犯血管造成短暂再通/闭塞。观察两组不同处理方法对再灌注心律失常的转复效果。结果:缺血后适应组再灌注心律失常的例数明显低于常规处理组(3/27vs12/29,P<0.05),术后心电图ST段回落值两组之间差异无统计学意义(P>0.05)。结论:缺血后适应处理能快速终止急诊PCI术中的再灌注心律失常。更多还原

【Abstract】 Objective:To explore whether ischemia postconditioning during emergency percutaneous intervention(PCI)can terminate reperfusion arrhythmia.Methods:Fifty-six patients with acute myocardial infarction undergoing primary PCI were randomized into the conventional treatment group(n=29)and postconditioning group(n=27).If reperfusion arrhythmia occurred,ischemic postconditioning(1 minute reperfusion followed by 1 minute occlusion)was conducted in postconditioning group and routine drug management or temporary pacing was taken in coventional group.Results:The number of reperfusion arrhythmia in postconditioning group was significantly lower than that in conventional treatment group(3/27 vs 12/29,P<0.05).There were no significant differences in ST segment regression between the two groups after PCI.Conclusion:The results suggest that ischemic postcoditioning can terminate reperfusion arrhythmia in patients with acute myocardial infarction undergoing emergency PCI.更多还原