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18F-FDG PET/CT显像在腮腺恶性肿瘤患者术后随访中的价值初探

Evaluation of effect of fluorine-18 fluorodeoxyglucose PET/CT imaging in patients with parotid carcinoma after surgery

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【作者】 杨忠毅施伟朱蓓玲章英剑

【Author】 YANG Zhong-yi,SHI Wei,ZHU Bei-ling,et al(Department of Nuclear Medicine,Cancer Hospital,Fudan University;Department of Oncology,Shanghai Medical College,Fudan University,Shanghai,200032,China)

【机构】 复旦大学附属肿瘤医院核医学科复旦大学上海医学院肿瘤学系

【摘要】 目的探讨18F-FDGPET/CT显像在腮腺恶性肿瘤术后患者随访中的临床应用价值。方法对12例腮腺恶性肿瘤术后患者(排除腮腺淋巴瘤及转移性肿瘤)的18F-FDGPET/CT显像资料进行回顾性分析,并将其与CT或MRI及随访结果进行比较。结果18F-FDGPET/CT显像对区域淋巴结转移的诊断灵敏度、特异性、准确率、阳性预测值和阴性预测值分别为100.0%、89.5%、91.7%、71.4%和100.0%,高于CT/MRI传统影像学检查的60.0%、68.4%、66.7%、33.3%和86.7%,且两者的准确率存在统计学差异(P<0.05)。此外,18F-FDGPET/CT显像诊断局部复发2例(1例假阳性),检出远处转移灶及其它病变各3例。结论18F-FDGPET/CT显像在腮腺恶性肿瘤术后患者的随访中有一定的意义,尤其对区域淋巴结转移的诊断有较高的价值。

【Abstract】 Objective To evaluate the effect of fluorine-18 fluorodeoxyglucose PET/CT imaging in postsurgical patients with parotid carcinoma.Methods Twelve post-surgical patients with parotid carcinoma were included in this retrospective study.The PET/CT imaging was analyzed in relation with the CT/MRI imaging and clinical follow-up results.Results The sensitivity,specificity,accuracy,positive predictive value and negative predictive value in detecting regional lymph nodes metastasis with fluorine-18 fluorodeoxyglucose PET/CT were 100.0%,89.5%,91.7%,71.4% and 100.0%,respectively.For CT/MRI imaging the corresponding values were 60.0%,68.4%,66.7%,33.3% and 86.7%,respectively.There was statistical difference between PET/CT and CT/MRI imaging for its accuracy(P<0.05).In addition,PET/CT detected 2 local recurrences(1 false positive case),3 distant metastasis and 3 unrelated lesions.Conclusion Fluorine-18 fluorodeoxyglucose PET is of value in evaluation of parotid carcinoma patients after surgery,especially for detecting regional lymph nodes metastasis.

  • 【文献出处】 实用肿瘤杂志 ,Journal of Practical Oncology , 编辑部邮箱 ,2010年02期
  • 【分类号】R739.87
  • 【被引频次】2
  • 【下载频次】103
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