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浮萍中黄酮类化学成分的分离与鉴定

Isolation and identification of flavonoids from whole plant of Spirodela polyrrhiza(L.)Schleid.

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【作者】 何文妮叶敏王宝荣高慧媛果德安吴立军

【Author】 HE Wen-ni1,2,YE Min2,WANG Bao-rong2,GAO Hui-yuan1,GUO De-an2,WU Li-jun1(1.School of Traditional Chinese Materia Medica,Shenyang Pharmaceutical University,Shenyang 110016,China;2.The State Key Laboratory of Natural and Biomimetic Drugs,School of Pharmaceutical Sciences,Peking University,Beijing 100191,China)

【机构】 沈阳药科大学中药学院北京大学药学院天然药物与仿生药物国家重点实验室

【摘要】 目的研究浮萍Spirodela polyrrhiza(L.)Schleid.的化学成分。方法采用正相和反相硅胶柱色谱以及半制备型HPLC进行分离纯化,根据理化性质和波谱数据鉴定化合物的结构。结果分离得到了5个黄酮苷类化合物,分别鉴定为芹菜素8-C-(2″-O-阿魏酰基)-β-D-葡萄糖苷(apigenin-8-C-(2″-O-feruoyl-)-β-D-glucoside,1),荭草素(rietin,2),牡荆素(vitexin,3),木犀草素7-O-β-D-葡萄糖苷(luteolin7-O-β-D-glucoside,4),芹菜素7-O-β-D-葡萄糖苷(apigenin7-O-β-D-glucoside,5)。结论化合物1为一个新化合物,化合物2和3为首次自该植物中分离得到。

【Abstract】 Objective To study the chemical constituents of the whole plant of Spirodela polyrrhiza(L.)Schleid..Methods The compounds were isolated by silica gel and ODS column chromatography and semi-preparative HPLC,their structures were elucidated on the basis of their physicochemical and spectroscopic data.Results Five compounds were obtained from S.polyrrhiza.Their structures were identified as apigenin 8-C-(2″-O-feruoyl)-β-D-glucoside(1),rietin(2),vitexin(3),luteolin 7-O-β-D-glucoside(4)and apigenin 7-O-β-D-glucoside(5).Conclusions Compound 1 is a new compound.Compounds 2 and 3 were isolated from this plant for the first time.

【基金】 教育部创新团队计划(No.985-2-063-112);北京大学医学部985项目(No.985-2-119-121)资助
  • 【文献出处】 沈阳药科大学学报 ,Journal of Shenyang Pharmaceutical University , 编辑部邮箱 ,2010年11期
  • 【分类号】R284
  • 【被引频次】19
  • 【下载频次】801
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