【摘要】 目的研究婴幼儿轮状病毒感染合并肝脏、心肌及神经系统等胃肠外脏器损害的关系。方法对254例住院腹泻患儿用金标法检测粪便轮状病毒抗原并做心肌酶及肝功检测,按照大便轮状病毒抗原检测结果分为观察组(大便轮状病毒抗原阳性)和对照组(大便轮状病毒抗原阴性),对其结果进行对比分析。结果观察组与对照组肝损害及心肌损害发生率比较差异有统计学意义(P<0.01),心肌损害及肝功能异常发生率与患儿发病年龄比较差异有统计学意义(P<0.01)。结论婴幼儿轮状病毒感染常合并心肌及肝损害,且年龄小者受损害几率较大,因此建议对轮状病毒感染患儿应常规完善心肌酶及肝功能检查,及时发现病情并给予有针对性的治疗。更多还原

【Abstract】 Objective To study the relationship between human rotavirus infection and parenteral damage in the liver,heart and nervous system in infants and young children.Methods 254 cases of hospitalized children with diarrhea were divided into observation group(stool rotavirus antigen positive) and control group(stool rotavirus antigen-negative) in accordance with the stool rotavirus antigen test results.The results were analyzed.Results Between the two groups,there was a significant difference(P<0.01)in liver damage and the incidence of myocardial damage.About the myocardial injury incidence of liver dysfunction in children with onset age,the difference was significant(P<0.01).Conclusion Rotavirus infection in infants often combined with cardiac and liver damage.The lower age,the larger risk of damage.It was proposed to be routine in children with rotavirus infection to perform the enzyme and liver function examination to improve the timely detection of the disease and provide the targeted therapy.更多还原