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地蒽酚蜡棒短程接触疗法联合窄谱中波紫外线治疗寻常型斑块状银屑病

Efficacy of dithranol wax sticks combined with NB-UVB in the treatment of psoriasis vulgaris

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【作者】 李洪武

【Author】 LI Hong-wu Department of Dermatology,Taian City Central Hospital,Taian 271000,China

【机构】 山东省泰安市中心医院皮肤科

【摘要】 目的观察地蒽酚蜡棒短程接触疗法联合窄谱中波紫外线(NB-UVB)治疗寻常型斑块状银屑病的疗效。方法 143例寻常型斑块状银屑病随机分为治疗组(地蒽酚蜡棒短程接触疗法联合NB-UVB组)49例,对照1组(地蒽酚蜡棒组)48例和对照2组(NB-UVB组)46例,连续治疗8周。结果 3组患者的基本治愈率分别为61.22%、39.58%和39.13%,总有效率分别为91.84%、77.08%和76.09%。治疗组分别与对照1组、对照2组比较,组间基本治愈率和总有效率均有显著性差异(P<0.05)。结论地蒽酚蜡棒联合NB-UVB治疗寻常型斑块状银屑病疗效优于单用地蒽酚蜡棒或单用NB-UVB组。

【Abstract】 Objective To evaluate the clinical efficacy of combined dithranol wax sticks and narrow-band ultraviolet B in the treatment of psoriasis vulgaris.Methods 143 patients with psoriasis vulgaris were randomly divided into three groups.Trial group was treated with dithrand wax sticks and narrow-band ultraviolet B (NB-UVB),control group 1 with dithrand wax sticks and control group 2 with NB-UVB.The patients in three groups all received 8 weeks of treatment.Results The cure rate of trial group,control group 1 and control group 2 was 61.22%,39.58% and 39.13% respectively.The effective rate was 91.84%,77.08% and 76.09% respectively.The difference between trial group and control groups was significant (P<0.05).Conclusions The combination of Dithranol wax sticks and NB-UVB is an effective ways for psoriasis treating,and its efficacy is higher than using dithranol wax sticks and narrow-band ultraviolet B alone.

  • 【文献出处】 实用皮肤病学杂志 ,Journal of Practical Dermatology , 编辑部邮箱 ,2010年04期
  • 【分类号】R758.63
  • 【被引频次】3
  • 【下载频次】66
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