【摘要】 目的 探讨视放射异常磁共振弥散张量成像(diffusion tensor imaging,DTI)、弥散张量纤维束追踪成像(diffusion tensor tractography,DTT)改变与视野缺损间的关系。方法 对37例脑内病变累及视放射的患者及20例正常对照组行3.0T磁共振DTI、DTT及视野检查,分析DTI的各向异性(FA)值、表观扩散系数(ADC)值与视野的平均光敏感度(MS)值及平均缺损(MD)值间的关系及视放射纤维束形态改变与视野缺损间的关系。结果 与对照组比较,病变组FA值降低、ADC值升高,差异均有统计学意义(P<0.001);病变组FA值与MS值呈正相关(r=0.718),与MD值呈负相关(r=-0.694);ADC值与MS值呈负相关(r=-0.625),与MD值呈正相关(r=0.538)。9例视放射腹束受损表现为双侧视野问上象限偏盲,7例背束及侧束受损表现为双侧视野同下象限偏盲;21例视放射广泛受损表现为双侧视野对称性或不对称性同向偏盲。结论 视放射DTI及DTT检查与视野检查结果有高度相关性,可成为评价视放射功能及形态改变的客观指标。更多还原

【Abstract】 Objective To study the relationship between the changes of diffusion tensor imaging(DTI) and diffusion tensor tractography(DTT)of optic radiation and the defect of visual field.Methods DTI and DTT were performed in 37 patients with invasion of the optic radiation by intracranial lesions and in 20 normal control group at 3.0T MR scanner,the visual fields of all cases were examined.The relativity between FA values,ADC values and mean sensitivity(MS) values,mean defect(MD) values of visual field and the relativity between the morphological change of optic radiation and the defect of visual field were analysed.Results In comparison with control group,FA values decreased and ADC values increased in subject group,there were statistically significant differences(P<0.001) between them.In disordered group,FA values were positive correlation with MS values(r=0.718) and negative correlation with MD values(r=-0.694);ADC values were negative correlation with MS values(r=-0.625) and positive correlation with MD values(r=0.538).DTT showed that the ventral tracts of optic radiation were damaged which oppeared as the defect of ditto quadrant of bilateral field vision in 9 cases,the dorsal tracts and the lateral tracts of optic radiation were damaged which appeared as the defect of inferior quadrant of bilateral field vision in 7 cases,the optic radiations were damaged extensively that caused symmetric or asymmetric congruous hemianopia of bilateral field vision in 21 cases.Conclusion DTI and DTT of optic radiation are intimately correlated with the examined results of visual field,it will be a objective index to extimate the function and the morphological changes of optic radiation.更多还原