【摘要】 目的 探讨常用聚乙烯醇(polyvinyl alcohol,PVA)颗粒经子宫动脉栓塞治疗子宫肌瘤的临床价值。方法 选择育龄期症状性子宫肌瘤患者共60例纳入研究对象。根据使用的PVA颗粒大小分为2组,研究组(A组)用300～500μm颗粒,对照组(B组)用500～700μm颗粒,每组30例。比较研究组及对照组术后疗效和对卵巢功能影响。结果 术后6月随访比较,(1)A组较B组临床症状改善更明显,差异有统计学意义(χ~2=6.213,P=0.013,P<0.05)。(2)A组及B组子宫肌瘤体积均缩小,但A组更显著,差异有统计学意义(t=8.613,P=0.001,P<0.05)。(3)术后6月内各组患者促卵泡刺激素水平在安全范围波动变化,未出现卵巢功能衰竭,差异无统计学意义(F=0.114,P=0.737,P>0.05)。结论 采用300～500μm PVA颗粒栓塞治疗子宫肌瘤安全可靠,临床疗效更好,具有临床推广价值。更多还原

【Abstract】 Objective To approach the clinical value of two general polyvinyl alcohol(PVA) in treating hysteromyoma by uterine arterial embolization(UAE).Methods 60 child-bearing period women with symptom hysteromyoma were involved in this study.They were divided into 2 groups according to the diameter of PVA embolism granulum,experimental group(group A) using 300～500μm PVA and control group(group B) using 500～700μm PVA,30 cases in each group.The therapeutic effect and the influence on ovarian function were analysed comparatively between the two groups.Results All cases followed-up for 6 months,which showed that:(1)The clinical symptoms of the patients in group A were improved obviously(χ~2=6.213,P=0.013,P<0.05);(2) The volumes of the tumors in all the patients were decreased,but were obvious in group A than group B(t=8.163,P<0.001,P<0.05);(3)The level of folliculin in all cases fluctuated in the safe limitation(F=0.114,P=0.737,P>0.05),without ovaries nonfunction.Conclusion The therapeutic effect using 300～500μm PVA is predominance and safety,that is worth to recommended in clinical practice.更多还原