【摘要】 目的:研究乳腺癌基质金属蛋白酶9表达与C-erbB-2表达间的相关性。方法:采用免疫组织化学法检测120例乳腺癌组织MMP9和C-erbB-2的表达。结果:120例乳腺癌组织中MMP9阳性表达率为62.5%(75/120),C-erbB-2阳性率为69.2%(83/120),其中C-erbB-2过表达阳性率为36.7%(44/120)。MMP9阳性表达与C-erbB-2过表达具有显著相关性。结论:MMP9阳性表达和C-erbB-2过表达与乳腺癌浸润转移相关,是乳腺癌预后指标。更多还原

【Abstract】 Objective:To study the relationship between the expression of MMP9 and the overexpression of C-erbB-2 in breast cancer.Methods:To detect the expression of MMP9 and C-erbB-2 in 120 specimens of breast cancer patients by the way of IHC.Results:The positive rate of MMP9 in 120 tumor specimens was 75(62.5%),positive rate of C-erbB-2 was 44(36.7%).The positive expression of MMP9 was correlated with overexpression of C-erbB-2 in breast cancer.Conclusion:There is a significant correlation between the expression of MMP9 and C-erbB-2 in breast carcinoma.They are both the prognotic factors in breast cancer.更多还原