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乳腺癌患者围手术期凝血功能的变化

Investigation of perioperative hemostatic alterations in patients with breast cancer

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【作者】 杨晓民任宏邓智平宋张骏李逢生马冬梅

【Author】 YANG Xiao-min1,2,REN-Hong1,DENG Zhi-ping2,SONG Zhang-jun2,LI Feng-sheng2,MA Dong-mei1 1The First Affiliated Hospital,Medicine School,Xi’an Jiaotong University,Xi’an 710061,China;2Department of Gynecology Oncology,Shaanxi Province Tumor Hospital,Xi’an 710061,China.

【机构】 西安交通大学医学院第一附属医院陕西省肿瘤医院

【摘要】 目的:研究乳腺癌术后患者血液凝血功能的变化。方法:随机选出50名(ASAⅠ-Ⅱ级)乳腺癌患者,分别测定手术前后凝血系列(FIB,TT,PT,APTT,ALT)。结果:乳腺癌患者术后FIB明显高于术前(P<0.05),APTT明显低于术前(P<0.05),PLT较术前增高(P<0.05)。结论:乳腺癌术后患者血液呈高凝状态,因而术后存在深部静脉血栓和肺栓塞的危险,及时预防治疗具有重要临床意义。

【Abstract】 Objective:To invest the change of perioperative hemostatic alterations in patients with breast cancer.Methods: To test the serial of perioperative hemostatic alterations(FIB,TT,PT,APTT,PLT)in 50 breast cancer patients(ASAⅠ-Ⅱgrade).Results: FIB and PLT of the patiets with breast cancer were higher preoperatively than that postoperatively(P<0.05),APTT obviously decreased postoperatively(P<0.05).Conclusion: Patients with breast cancer in postoperative stage were in hypercoagulabale state(HCS),consequently,deep vein thrombosis(dvt) and lung embolism may develop,prevention and therapy in time are important.

【关键词】 乳腺癌高凝状态血栓
【Key words】 breast cancerhypercoagulabale statethrombus
  • 【文献出处】 现代肿瘤医学 ,Journal of Modern Oncology , 编辑部邮箱 ,2010年04期
  • 【分类号】R737.9
  • 【被引频次】5
  • 【下载频次】181
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