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低度恶性纤维黏液样肉瘤的临床病理特征
Clinicopathologic study of two patients with low grade fibromyxoid sarcoma
【摘要】 目的:了解低度恶性纤维黏液样肉瘤的临床病理特征。方法:收集2例低度恶性纤维黏液样肉瘤的临床资料,手术切除组织光镜切片观察,另作9项免疫组织化学标记,CKp,EMA,Vimentin,SMA,MSA,CD34,CD99,S-100,CD68。结果:2例男女各1例,肿瘤由梭形细胞区和星形细胞黏液样区构成,1例有典型的巨形菊形团样结构。肿瘤呈浸润性生长,易复发。免疫组织化学标记瘤组织CKp,EMA,Vimentin,SMA,MSA,CD34,CD99,S-100,CD68阴性,Vimentin阳性。结论:低度恶性纤维黏液样肉瘤的诊断靠病理组织学和免疫组织化学标记,手术切除为主要的治疗方法。
【Abstract】 Objective:To investigate the clinicopathological features of low grade fibromyxoid sarcoma.Methods:By means of histological and immunohistochemical studies,the clinical and pathological features of two cases of low grade fibromyxoid sarcoma were analyzed.Results:Patients were 19 years old male and 65 years old female.The tumors were located the left back of neck and left chest wall.Immunohistochemical expression of Vimentin was positive,and CKp,EMA,SMA,MSA,CD34,CD99,S-100,CD68 were negative.Conclusion:The low grade fibromyxiod sarcoma is a rare tumor.The diagnosis was based on histological and immunohistochemical staining.
【Key words】 low grade fibromyxoid sarcom; immunohistochemistry; microscopy; giant rosettes;
- 【文献出处】 现代肿瘤医学 ,Journal of Modern Oncology , 编辑部邮箱 ,2010年02期
- 【分类号】R738
- 【被引频次】4
- 【下载频次】131