【摘要】 细胞打印技术是一种在体外构造具有生物活性的三维多细胞体系的先进技术。近年来,有关细胞打印技术的研究引起广泛的关注,其原因在于该领域具有明显的学科交叉与渗透融合的特点,它处于生命科学与快速成型技术、生物制造技术、生物科学和材料科学的交汇点。更加值得关注的是它为组织工程学突破二维研究的局限性,在三维尺度上精确控制与人体组织或器官相似的三维构造体方面的研究提供了一种新的思路。基于这一技术不仅在三维组织工程,还对细胞生物学、高通量药物筛选及细胞传感器等方面的前沿问题均有广阔的研究应用前景,介绍了近年来开发用于细胞打印的技术及其潜在的应用。更多还原

【Abstract】 Cell bioprinting can be defined as an advanced technology that fabricates 3D functional multi-cellular tissue in vitro.Due to its interdisciplinary characteristics,high resolution,cell bioprinting has been of considerable importance and popularity in recently.It is a powerful technology for tissue engineering and biological studies.Rather than a single approach,cell bioprinting includes a set of techniques(e.g.inkjet bioprinting,laser based techniques)that transfer biologically materials onto a substrate.Cell bioprinting also provides a new concept that how to construct more naturally 3D tissues or organs in vitro.The principle of these techniques was introduced,An overview of cell bioprinting in biological engineering applications,such as building 3D micro tissue,investigating cell biology,fabricating cell based microarray was also presented.更多还原