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百里香酚的抗肿瘤作用

Antitumor efficacy of thymol

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【作者】 殷清华庄英帜严奉祥

【Author】 YIN Qing-hua1, ZHUANG Yin-zhi1, YAN Feng-xiang2 (1 Department of oncology of the first affiliated hospital of University of South China, 421001, Hengyang China; 2 Institute of Pharmacy & Pharmacology, University of South China,421001, Hengyang China)

【机构】 南华大学附属第一医院肿瘤内科南华大学药物药理研究所

【摘要】 目的:观察百里香酚对体外培养的肝癌细胞的抑制作用。方法:体外培养人肝癌细胞(Bel-7402),采用MTT法、AO/EB荧光染色法观察百里香酚对人肝癌细胞Bel-7402的作用。结果:百里香酚可显著抑制Bel-7402细胞的生长;经百里香酚作用后,肝癌细胞在显微镜形态明显改变。结论:百里香酚能抑制肝癌Bel-7402细胞生长。

【Abstract】 Objective:To investigate the effect of thymol on human liver cancer cell (Bel-7402) in vitro cultured.Methods:Bel-7402 was cultured in vitro.The effect of thymol at different concentrations on human hepatocellular carcinoma (HCC)cell line Bel-7402 was detected by MTT assay, acridine orange (AO)/ethidiumbromide (EB)florescent staining.Results:Thymol could significantly inhibit the growth of HCC cells in vitro.After treatment with thymol, there were significantly changes for the morphology of the human hepatocellular carcinoma cell.Conclusion:Thymol acts on cancer through inhibiting the proliferation of Bel-7402.

【关键词】 百里香酚肝癌Bel-7402细胞抗癌
【Key words】 ThymolLiver cancer Bel-7402 cellAnti-cancer
  • 【文献出处】 现代生物医学进展 ,Progress in Modern Biomedicine , 编辑部邮箱 ,2010年11期
  • 【分类号】R285.5
  • 【被引频次】39
  • 【下载频次】448
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