【摘要】 目的提高经鼻蝶鞍区病变手术的安全性。方法回顾性分析经鼻蝶显微手术切除的196例鞍区病变的临床资料,结合文献加以讨论。结果病变全切168例,次全切26例,2例未切除。术后永久性尿崩2例,术后出血3例,脑脊液鼻漏21例,脑膜炎8例。视力障碍加重5例。本组死亡5例(2.55%)。结论准确的术前诊断、细致的影像学资料分析、术中神经导航的应用、娴熟的显微手术技术以及术后并发症的积极防治可以大大提高经鼻蝶鞍区病变手术的安全性。更多还原

【Abstract】 Objective To further improve the safety of surgery for lesions in sellar region.Methods Clinical data of 196 patients undergoing transsphenoidal microsurgery for lesions in sellar region and the related literatures were reviewed to evaluate safety and management.Results A total of 168 cases were totally removed,26 cases were sub-totally removed,and 2 cases could not be removed.After operation hemorrhagic complication occurred in 3 cases,permanent diabetes insipidus in 2 cases,cerebrospinal fluid rhinorrhea in 21 cases,meningitis in 8 cases,and visual disorder aggravation in 5 cases.The mortality of this group was 2.55%(5 cases).Conclusion Accurate preoperative diagnosis,careful analysis of clinical data,application of neuronavigation and microsurgical skills and the treatment of complications can greatly improve the safety of surgery for lesions in sellar region.更多还原