【摘要】 目的研究巨大脑动静脉畸形(AVM)手术切除后的脑皮质血流变化,指导临床降压治疗及血压监测等。方法AVM直径>6 cm的患者26例,用激光多普勒血流仪(LDF)分别记录切除AVM前、术后即刻、术后1 d、术后2 d、术后3 d的脑血流值,比较血流变化情况,观察术后脑血流稳定和再灌注水平下降所需时间。结果巨大脑AVM切除后脑局部的皮层血流较术前立即增高(P<0.05),术后2 d与术后1 d、术后即刻比较均无明显改变(P>0.05);术后3 d较术后2 d有所降低(P<0.05)。讨论巨大AVM切除后局部脑组织的血流明显增加,术后2 d达最高,术后3 d开始有明显的下降,但尚未达到术前的水平。更多还原

【Abstract】 Objective To investigate pre-and post-operative changes of regional cerebral cortical blood flow in patients with giant cerebral arterioneous malformation(AVM).Methods Twenty-six adult patients with giant AVM were entered into this study.The diameter of AVM was more than 6 cm.Cortical blood flow(CBF) was measured by using laser Doppler flowmeter(LDF) at before,after AVM resection,1,2 and 3 days after operation.Results The CBF increased immediately after AVM resection and continued for 3 days after operation(P<0.05).The CBF decreased obviously at the 3rd day after operation than that of previous day(P<0.05).Conclusion The CBF of giant AVM after AVM resection increased obviously especially at the 2nd day after operation.The CBF decreased at the 3rd post-operative day yet still higher than operation before.更多还原