【摘要】 目的研究外用重组碱性成纤维细胞生长因子冶疗供皮区创面的最佳用药方法,以指导临床应用。方法设生理盐水治疗为对照组,选择3种bFGF用法(每日1次法,每日3次法,每日1次加保湿法),进行供皮区创面愈合的比较性研究。结果和对照组相比,bFGF可有效促进供皮区创面愈合(P<0.01)。3种用药方法之间比较,差异具有统计学意义(P<0.05),1次/d加保湿法和3次/d法均能进一步缩短创面愈合时间。结论从方便、经济与合理的角度考虑,1次/d加保湿法为临床首选。更多还原

【Abstract】 Objective To explore the best method of applying basic fibroblast growth factor on skin graft donor site for the purpose of to guide its clinical application.Methods The skin graft donor sites were treated by bFGF with three different application methods(once a day,three times a day and once a day with molstenmg).Normal saline was employed as the self-control agent.The wound healing time in each method was was recorded and compared with each other.Results When compared with the self-control agent.the wound healing time was much shorter with bFGF application(P<0.01).There were also obvious differences in the wound healing time with different methods(P<0.05).In addition,once a day,with moistening and three times a day of bFGF application cound further shorten the wound healing time.Conclusion In view of the convenicnce,economy and feasibility,once a day with moistening is recommended for the bFGF clinical application.更多还原