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中国云南白族和新疆维族7个Y-STR基因座的遗传多态性
Genetic Polymorphism of 7 Y-STR Loci in the Yunnan Bai and Xinjiang Uygur Peoples of China
【摘要】 利用AB I3100遗传分析仪,我们调查了7个Y-STR基因座构成的单体型在中国云南白族133例和新疆维族105例无关男性个体中的分布。7个Y-STR基因座包括DYS456、DYS464 a/b/c/d、DYS527 a/b、DYS531、DYS709、DYS448和DYS522。结果显示,云南白族和新疆维族2个民族男性群体中,分别观察到133、105种单体型,均为仅观察到1次的单体型,单体型多样性(HD)均趋近于1,比较这种单体型在两个群体中的分布差异,显示有统计学显著意义(秩和检验:P<0.001)。中国云南白族和新疆维族7个Y-STR基因座具有较高的多态性,为法医学实践和群体遗传学的研究提供了有用的基础资料。
【Abstract】 Using the ABI 3100 genetic analyzer,we investigated the haplotype distribution of 7 Y-STR loci among 133 unrelated Bai males in Yunnan Province and 105 unrelated Uygur males in Xinjiang.The 7 Y-STR markers include DYS456,DYS464a/b/c/d,DYS527a/b,DYS531,DYS709,DYS448 and DYS522.The results revealed 133 and 105 haplotypes of 7 Y-STR loci in these two Chinese minority populations,respectively,with each haplotype appearing only once,making the haplotype diversity almost 1 for both groups.The distribution pattern of 7 Y-STR haplotype between these two ethnic groups was found to be statistically significant(P<0.001).These highly polymorphic loci will prove to be useful for forensic identifications and for populational genetic studies.
【Key words】 Y chromosome; Short tandem repeat; Haplotype; Genetic polymorphism;
- 【文献出处】 人类学学报 ,Acta Anthropologica Sinica , 编辑部邮箱 ,2010年01期
- 【分类号】Q987
- 【被引频次】5
- 【下载频次】210