【摘要】 目的应用定量组织速度显像评价急诊经皮冠状动脉介入术(PCI)治疗对急性心肌梗死(AMI)患者左室收缩和舒张功能的影响。方法本研究共入选22例急性ST段抬高性心肌梗死患者,于急诊PCI治疗前及治疗后1周、3个月、6个月分别测定患者的左房室瓣环收缩期峰值速度(Sa)、舒张早期峰值速度(Ea)和舒张晚期峰值速度(Aa),并计算Ea/Aa比值。结果(1)PCI治疗后1周患者Sa与治疗前比较差异无统计学意义(q=0.515,P<0.05);PCI治疗后3、6个月患者Sa较治疗前有所升高,差异均有统计学意义(q值分别为0.042和0.029,P<0.05);PCI治疗后3个月与治疗后1周时比较Sa也有所升高,差异有统计学意义(q=0.012,P<0.05)。(2)急诊PCI治疗后3、6个月患者Ea与治疗前比较有所升高,差异均有统计学意义(q值分别为0.012和0.011,P<0.05)。(3)急诊PCI治疗后1周、3个月和6个月患者Ea/Aa比值与治疗前比较有所升高,差异均有统计学意义(q值分别为0.023、0.018和0.012,P<0.05)。结论急诊PCI治疗可以改善AMI患者的左室收缩和舒张功能;定量组织速度显像可以准确、敏感地评价AMI患者急诊PCI治疗后左室收缩和舒张功能变化。更多还原

【Abstract】 Objective To evaluate the clinical value of quantitative tissue velocity imaging in detecton of left ventricular systolic and diastolic function in patients with acute myocardial infarction (AMI) after primary percutaneous coronary intervention.Methods The velocuties of peak systolic flow velocity (Sa) of left atrioventricular valve ring,early diastolic peak velocity (Ea) and late diastolic peak velocity (Aa) were determined in 22 patients with AMI ST segment elevation before emergency PCI treatment or 1 week,months 3,6 after.Ea/Aa ratio was calculated.Results No significant difference was noted in Sa between post- and pre-PCI treatments(q=0.515,P<0.05).Sa increased 3,6 months after PCI treatment as compared with pre-treatment,the difference was significant(q=0.042,0.029,P<0.05).Sa was higher 3 months after treatment than 1 week after treatment (q=0.012,P<0.05).Ea was higher 3,6 months after emergency PCI treatment than before (q=0.012,0.011,P<0.05).Ea/As ratio increased 1 week,months 3,6 after emergency PCI treatment when compared with pre-treatment (q=0.023,0.018,0.012,P<0.05).Conclusion Emergency PCI treatment can improve left ventricular systolic and diastolic functions in AMI patients.Quantitative tissue velocity imaging can evaluate accurately and sensitively the changes of systolic and diastolic functions after emergency PCI treatment.更多还原