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子宫内膜息肉发病的相关因素研究

Factors Associated with Pathogenesis of Endometrial Polyps

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【作者】 罗雪梅程秋蓉孟晓军杨明艳杜建林

【Author】 LUO Xue-mei,CHEN Qiu-rong,MENG Xiao-jun,et al.Medical College of Jishou University,Jishou 416000,China

【机构】 吉首大学医学院吉首大学附属第一医院中山大学附属第五医院

【摘要】 目的探讨子宫内膜息肉(EP)发病的相关因素。方法对具有异常子宫出血、不孕、宫颈息肉、体检超声提示子宫内膜息肉的359例妇女行阴道B超和宫腔镜检查,并记录患者的临床资料,用SPSS统计软件进行单因素及多因素非条件Logistic回归分析。结果单因素分析显示对子宫内膜息肉发病有统计学意义的因素有孕次、绝经、口服避孕药、近期激素治疗史、慢性子宫内膜炎、宫颈息肉、肥胖、高血压和糖尿病,将以上因素做为因变量进行多因素Logistic回归分析,结果显示绝经、口服避孕药、子宫内膜炎和宫颈息肉对子宫内膜息肉发病有明显影响(P<0.05),其OR值分别为8.38、0.19、8.79和2.94。结论绝经、子宫内膜炎和宫颈息肉均为EP发病的相关危险因素;口服避孕药为子宫内膜息肉的保护因素。

【Abstract】 Objective To identify factors associated with pathogenesis of endometrial polyps(EP).Methods A total of 359 EP women diagnosed by ultrosonography during health examination were given transvaginal B-ultrosonography and hysteroscopy because of abnormal uterine bleeding,or infertility,or cervical polyps.Their clinical data were recorded and analyzed by univariable logistic analysis and unconditional logistic regression on the software of SPSS.Results Univariable logistic analysis showed a statistically significant association with gravidity time,menopause,oral contraceptive,recent history of hormonal therapy,chronic endometritis,cervical polyps,obesity,hyperpiesia and diabetes mellitus.However,as these factors were taken as the dependent variables,multivariable logistic regression analysis showed only menopause,oral contraceptive,chronic endometritis and cervical polyps entered the logistic equation by statistic significance(P<0.05),with their OR values being 8.38,0.19,8.79 and 2.94,respectively.Conclusion menopause,chronic endometritis and cervical polyps are the risk factors,while oral contraceptive is the protective factor for EP.

【关键词】 子宫内膜息肉病理学Logistic模型
【Key words】 Endometrial polypsPathologyLogistic model
【基金】 湖南省自然科学基金项目(07JJ6030)
  • 【文献出处】 中国全科医学 ,Chinese General Practice , 编辑部邮箱 ,2010年06期
  • 【分类号】R711.74
  • 【被引频次】92
  • 【下载频次】1347
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