【摘要】 目的研究和评价骶骨肿瘤术前经导管超选择性动脉栓塞的价值和作用。方法将36例骶骨肿瘤术前行动脉栓塞患者作为观察组,随机选择直接行手术切除的骶骨肿瘤患者30例作为对照组。就术中出血量及手术时间进行对比研究。结果 32例患者栓塞后造影均显示肿瘤血管、肿瘤染色明显减少,较栓塞前减少90%以上。全部病例均在栓塞后24h内手术,术中失血量为(1062±221.67)ml,手术时间为(158.26±47.83)min,与对照组比较,差异有统计学意义(P<0.01)。经栓塞后肿瘤组织均有不同程度的坏死、液化和囊性变,部分肿瘤边缘有假包膜形成。结论超选择性动脉栓塞术治疗骶骨肿瘤能有效地减少术中出血,降低手术的危险性,提高肿瘤手术切除率,是一种十分有效的方法 。更多还原

【Abstract】 Objective To study and evaluate the efficacy and safety of transcatheter preoperative superselective arterial embolization of sacral tumor. Methods 36 patients with sacral tumors were embolized preoperatively and their clinical improvement was observedafter the embolization,as observer group. Another 30 patients with sacral tumors who didn’t receive preoperative embolization therapy were used as control group. The blood loss and the time spent during operation were counted. The results in two groups were compared with each other. Results The therapeutic result showed that the proportion of tumorstain was markedly reduced after embolization by 90% or more,all tumor were resected in 24 hours after embolization. The blood loss during the operation was (1062 ± 221. 67)ml and the time spent during the operation was (158. 26 ± 47. 83)min,compared with the control group,the difference were statistically significant (P < 0. 01). The histological results confirmed that necrosis,liquefaction,cystic degeneration and the formation of pseudocapsule in all tumors occurred,despite of their varying degrees. Conclusion This technique is an effective and safe method in decreasing intraoperative blood loss with good surgical result.更多还原