226例新生儿溶血病ABO血型不合的检测与分析研究

【摘要】 目的:探讨由母婴ABO血型不合引起的新生儿溶血病(HDN)的血型分布及其溶血三项检测试验的重要性。方法:对226例临床新生儿溶血病进行ABO新生儿溶血(HDN)血清学检测,包括直接抗人球蛋白试验、红细胞抗体释放试验、血清游离抗体试验。结果:在226例临床新生儿溶血病中由ABO血型抗原不合引起的新生儿溶血病138例,占送检标本的61.06%,其抗体释放试验均为阳性,A型患儿为63例,阳性率45.65%,B型患儿为75例,阳性率54.35%。结论:ABO血型不合引起的新生儿溶血病检测以抗体释放试验阳性为确诊试验,ABO新生儿溶血病的明确诊断可为临床诊疗及预防提供可靠依据。更多还原

【Abstract】 Objective: To investigate the blood type distribution in the ABO blood group incompatibility caused hemolytic disease of newborn and check the efficiency of the hemolytic test. Methods: Serum analysis method of blood groups was used to detect hemolytic disease of newborn (HDN) about 226 cases in clinical, including direct Coombs Test, red blood cell antibody release test, and serum free antibody test. Results: There were 138 cases caused by ABO blood groups antigen incompatibility in 226 cases of hemolytic disease of newborns in clinical, accounting for 61.06% of specimens submission (138/226), the antibodies release test was positive, A-type patients, 63 cases, the positive rate of 45.65 % (63/138), B type, 75 patients, the positive rate of 54.35% (75/138). Conclusion: ABO hemolytic disease in newborns due to release test positive antibody test for the diagnosis, ABO hemolytic disease of newborn diagnosis can provide a reliable basis for clinical treatment, for treatment time.更多还原